Physical Growth in Children with Transfusion Dependent Thalassemia

نویسندگان

چکیده

Background: Thalassaemia is a major congenital hematological disease of Bangladesh. Poor growth and delayed maturation occurs in these patients commonly. This study was aimed to evaluate the physical Transfusion Dependent Thalassemia (TDT).
 Materials methods: cross-sectional comparative enrolled 60 diagnosed Children with dependent over I year carried out Pediatric Hematology Oncology unit Department Chittagong Medical College Hospital, Chattogram. Among them, 30 children received blood transfusion >12 times per considered as group rest £12 II. Statistical analysis done by using window based computer software devised Packages for Social Sciences (SPSS-22).
 Results: The mean serum ferritin higher than II(1243.77±761.626 293.77±142.686 respectively). Almost two third (60.0%) were severely stunted 8(26.7%) 28(93.3%) had under weight (<-2SD) 18(60.0%) difference statistically significant between groups.
 Conclusion: Growth retardation (Height age) number level .
 JCMCTA 2021 ; 32 (1) : 89-95

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Osteoporosis-osteopenia syndrome in children with transfusion dependent thalassemia

Background Osteoporosis-osteopenia syndrome (OOS) is found in more than 50% of thalassemia patients worldwide [1,2]. Despite appropriate management, thalassemics continue to exhibit a decrease in bone mass due to the multifactorial pathogenesis of OOS in thalassemia [3]. Therefore, this study aims to obtain an insight on the thalassemia patients' perception of OOS and possible lifestyle contrib...

متن کامل

Zinc Supplementation Effect on Linear Growth in Transfusion Dependent β Thalassemia

Objective: Thalassemic patients are at risk of zinc deficiency due to various causes including desferal injection, hyperzincuria, high ferritin levels, and hepatic iron overload. We evaluate the effect of zinc supplementation on linear growth of beta-thalassemia patients. Methods: one-hundred beta-thalassemic major patients whose heights were within 3rd to l0th percentile were randomly divided ...

متن کامل

Bone density in transfusion dependent thalassemia patients in Urmia, Iran

Background Patients with thalassemia major and intermedia are susceptible to osteopenia and osteoporosis. The mechanism of osteoporosis in these patients is multifactorial. Transfusion related iron overload in endocrine organs leads to impaired growth hormone secretion, diabetes mellitus, hypothyroidism, hypoparathyroidism, lack of sex steroids and vitamin D deficiency that contribute t...

متن کامل

Prevalence of Alloantibodies and Autoantibodies in Transfusion Dependent Thalassemia Patients

Background: The development of anti-red blood cell alloantibodies remains a major problem in transfusion of blood in thalassemia major patients. Also, Autoantibodies can result in clinical hemolysis and difficulty in cross-matching blood. We studied the frequency of red blood cell alloimmunization and autoimmunization among thalassemia patients who received regular transfusions in Ilam province...

متن کامل

Extramedullary Hematopoiesis in a Patient with Transfusion Dependent Beta-Thalassemia Presenting with Cord Compression

Extramedullary hematopoiesis (EMH) is a physiological compensatory phenomenon occurring in many hemolytic anemias including thalassemia. Besides transfusion, radiotherapy, surgery or a combination of these modalities, hydroxyurea (HU) as an optimal treatment has been described occasionally. We described a case of beta-thalassemia major who has been on regular blood transfusion and developed EMH...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Chittagong Medical College Teachers' Association

سال: 2021

ISSN: ['1609-1558', '2224-7300']

DOI: https://doi.org/10.3329/jcmcta.v32i1.66563